1. Idiosyncratic reactions
  2. Allergic reactions
  3. Toxic effects 
  4. Side effects 
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1 Answers

Option 1 : Idiosyncratic reactions

Concept:

  • Idiosyncratic reactions these are the adverse effects that cannot be explained by known mechanisms
  • Idiosyncratic drug reactions are a significant cause of morbidity and mortality for patients; they also markedly increase the uncertainty of drug development.
  • The major targets are skin, liver, and bone marrow.
  • Clinical characteristics suggest that IDRs are immune mediated
  • For example a patient with monoclonus infection developed rashes immediately after administration of ampicilline

 

  • Allergic reactions are most common side effects of all the drugs which includes skin rashes, erythematous skin lesions
  • Drug toxicity can damage the organ or entire system of a person the common toxic reactions include anxiety, restlessness, hallucinations, high temperature, chest pain etc.,
  • Close observation and exact drug calculation is required to avoid such drug toxicity
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