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Option 2 : Vitamin B12
Concept:-
- Gastritis is an inflammation, irritation, or erosion of the lining of the stomach. It can occur suddenly (acute) or gradually (chronic).
- Chronic gastritis causes deterioration and atrophy of the stomach lining, leading to loss of function of the parietal cells.
- The source of intrinsic factor is lost, resulting in an inability to absorb vitamin B12. This leads to the development of pernicious anemia.
- Autoimmune gastritis (pernicious anemia) is the most common cause of severe vitamin B12 deficiency due to food-cobalamin spoilage in the elderly, yet the use of medications, such as proton pump inhibitors, histamine H2 blockers, metformin, or cholestyramine, are vitamin K. can interfere with or reduce. B12 absorption.
- The most common are vitamin B12 deficiency, which results in megaloblastic anemia and iron deficiency, leading to iron deficiency anemia.
- Deficiency in the level of intrinsic factors leads to malabsorption of vitamin B12. Indeed, intrinsic factor has an important role in binding vitamin B12 in the duodenum and transporting it to the terminal ileum for absorption.
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