Which of the following ways is NOT mediated by MHC antigens in order to showcase diversity of antigen presentation?
Which of the following ways is NOT mediated by MHC antigens in order to showcase diversity of antigen presentation? Correct Answer By expression of same allele within same species
MHC is polygenic in nature and its expression is codominant. MHC genes are also polymorphic in nature therefore they vary from organism to organism. As a result, expression of same allele within same species is not possible and it is against the nature of MHC gene. Sexual selection has been observed in male mice mating with female mice having different MHCs. It has been observed that, for MHC I presentation, antigenic peptide splicing takes place resulting in binding to peptides of different proteins thereby increasing the antigenic diversity.
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Feb 20, 2025