Which antigens bind to antigen-presenting cells for their presentation through mannose receptor?
Which antigens bind to antigen-presenting cells for their presentation through mannose receptor? Correct Answer Lipoglycan antigens
Lipoglycan antigens are the non-peptide antigens which bind to APCs (Antigen Presenting Cells) with the help of pattern recognition molecules like mannose receptor and CD14. They follow endosomal pathway which helps the lipoglycan antigens to bind to CD1. They further form antigen-CD1 complex where the actual recognition takes place.
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Feb 20, 2025