Immunology MCQ 126+

Test your knowledge with important Immunology MCQ and their applications. These MCQs are beneficial for competitive exams too. Explore 156 + more Immunology MCQs at Bissoy

• Which of the following is the most important Fluorescent Protein used in Flow Cytometry?
  ক

  FITC

  খ

  PE

  গ

  GFP

  ঘ

  APC
• What is physiological buffer used in flow cytometer called as?
  ক

  Sheath fluid

  খ

  Fluorescent fluid

  গ

  Chemical fluid

  ঘ

  Stream fluid
• Which of the following is NOT a component of flow cytometer?
  ক

  Fluidics system

  খ

  Optical system

  গ

  Electronic system

  ঘ

  Chemical system
• Which of the following is NOT considered as a parameter for their analysis by Flow Cytometry?
  ক

  Functional analysis

  খ

  Cell viability

  গ

  Clonality

  ঘ

  Cell cycle analysis
• What are fluorescent molecules and fluorescent dyes also termed as?
  ক

  Fluorophores

  খ

  Molephores

  গ

  Fluorescent molephores

  ঘ

  Cytochromes
• Flow cytometry is used to for which cell population?
  ক

  Homogenous population of cells

  খ

  Heterogeneous population of cells

  গ

  Both homogenous and heterogeneous population of cells

  ঘ

  Heterotopic population of cells 
• Changes in cell shape, the loss of its structure and cell detachment occurs due to which of the following reason?
  ক

  Irregularity in cell cycle

  খ

  Apoptosis

  গ

  Error in cell’s viability

  ঘ

  Drop in the level of biological activity of cell
• Which of the following dye conjugate is termed to be the high-performance conjugate for the use of flow cytometry?
  ক

  Tide FluorTM

  খ

  Tide QuencherTM

  গ

  DyLightTM

  ঘ

  KLH
• Primary type of IF (immunofluorescence) technique uses two antibodies in association with fluorescent dye.
  ক

  True

  খ

  False
• What is another term for Immunofluorescence?
  ক

  Cell imaging

  খ

  Imaging antibodies

  গ

  Fluorophores

  ঘ

  Antigen imaging
• What is the optimal range (moles/lit) for proteins to be detected by ELISA assay?
  ক

  102 to 106 moles/lit

  খ

  10-12 to 10-9 moles/lit

  গ

  1012 to 109 moles/lit

  ঘ

  10-2 to 10-6 moles/lit
•  Which of the following is NOT an advantage of Sandwich ELISA?
  ক

  Offers high sensitivity compared to direct or indirect ELISA

  খ

  Introduces highly specific reaction due to the involvement of two antibodies for antigen detection

  গ

  Both direct and indirect technique is implemented in detection

  ঘ

  It is cheaper as there is a requirement of fewer labelled antibodies
• Which of the following is NOT a type of data output expected in ELISA assay?
  ক

  Quantitative analysis

  খ

  Qualitative analysis

  গ

  Semi-quantitative analysis

  ঘ

  Semi-qualitative analysis
• Which antibodies are used for ELISA technique?
  ক

  Primary antibodies

  খ

  Secondary antibodies

  গ

  Primary as well as secondary antibodies

  ঘ

  Primary, secondary and tertiary antibodies
• Immobilisation of antibody-antigen is mediated by which type of interaction?
  ক

  Hydrophilic interaction

  খ

  Hydrophobic interaction

  গ

  Non-covalent interaction

  ঘ

  Chemical interaction
• Which of the following is an important disadvantage of Indirect ELISA?
  ক

  Optimization in terms of antibody becomes problematic due to cross-reactivity issues

  খ

  Higher signal to noise ratio results in issues of accuracy

  গ

  For recognition of a specific epitope, only monoclonal antibodies can be applied as matched pairs

  ঘ

  Offers less flexibility in terms of primary antibody
• Which of the following ELISA kits are available for specific purposes?
  ক

  Antibody pair kit and Instant ELISA kit containing post-coated antibody plates

  খ

  Inferior ELISA kit and Antigen pair kit

  গ

  Antibody pair kit and Instant ELISA kit containing pre-coated antibody plates

  ঘ

  Instant ELISA kit and Inferior ELISA kit
• With which of the following enzyme, labelling of antibodies is carried out in Direct ELISA detection technique?
  ক

  Alkaline Phosphatase

  খ

  Hyaluronidase

  গ

  Lactase

  ঘ

  Amylase
• ELISA is divided into 4 categories namely: Direct, Indirect, Competition and Supplementary ELISA.
  ক

  True 

  খ

  False
• Which of the following disease is NOT diagnosed by ELISA?
  ক

  Lyme disease

  খ

  Rotavirus

  গ

  Syphilis

  ঘ

  Flu
• What does ELISA stand for?
  ক

  Enzyme-linked immunodeficient sorbent assay

  খ

  Enzyme-linked immunosorbent assay

  গ

  Enzyme-linked immune sorbent assay

  ঘ

  Enzyme-linked immunity scientific assay
• Latex test is popular to detect antigen of which fungus?
  ক

  Cryptococcus neoformans

  খ

  Basidiomycetes

  গ

  Blastocladiomycota

  ঘ

  Hypomycetes
• Which form of agglutination is used in blood typing?
  ক

  Particle agglutination

  খ

  Hemagglutination

  গ

  Latex agglutination

  ঘ

  Tube agglutination
• Which type of agglutination reaction is used routinely for serological diagnosis of typhoid?
  ক

  Tube agglutination

  খ

  Active agglutination

  গ

  Passive agglutination

  ঘ

  Slide agglutination
• What is the approximate incubation period for the procedure of Widal test for testing typhoid bacterial cell?
  ক

  15 minutes at 37°C

  খ

  30 minutes at 37°C

  গ

  60 minutes at 35°C

  ঘ

  30 minutes at 35°C
• Immunoprecipitation was developed in relation to which of the following mechanism?
  ক

  Supercritical Chromatography

  খ

  Gas Chromatography

  গ

  Reversed Phase Chromatography

  ঘ

  Affinity Chromatography
• How is the positive result indicated in slide agglutination reaction?
  ক

  Visibility of separate particles

  খ

  Clumping of the particles

  গ

  Colour change

  ঘ

  Wavelength difference is seen
• To perform latex agglutination, by what should the specimens be treated before testing?
  ক

  Latex solution

  খ

  EDTA

  গ

  Conc. HCL

  ঘ

  Sodium chloride solution
• Antibodies that produce agglutination reactions are called as glutinins.
  ক

  True

  খ

  False
• Which of the following is NOT a type of agglutination reaction?
  ক

  Slide agglutination

  খ

  Active agglutination

  গ

  Passive agglutination

  ঘ

  Tube agglutination