In the case of MHC 2-restricted presentation, where do the antigens degrade?
In the case of MHC 2-restricted presentation, where do the antigens degrade? Correct Answer Endosomal/Lysosomal compartments
The cross-presentation of antigens on MHC-2 molecules is less understood as it leads to a completely different pathway of mechanism. However, the recent study shows that the antigens which get internalized are degraded to endosomal or lysosomal compartments with the help of certain proteases like cathepsins.
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Feb 20, 2025