Which among the following is a high affinity ligand for retinoic acid receptors (RARs)?

Which among the following is a high affinity ligand for retinoic acid receptors (RARs)? Correct Answer All-trans-retinoic acid

Vitamin A is processed in the liver and is activated by all-trans-retinoic acid metabolism, which is a high-affinity retinoic acid receptor (RAR)ligand. In paracrine as well as endocrine pathways, 9-cis-retinoic acid is likely to act as a signaling molecule.
Bissoy MCQ

Related Questions

Receptor R is over expressed in CHO cells and analyzed for expression. 6 × 107 cells were incubated with its radioactive ligand (specific activity 100 counts per picomole). If the total counts present in cell pellet was 1000 cpm. the average number of receptors R per cell is (assume complete saturation of receptors with ligand and one ligand binds to one receptor)
In a batch process, the reaction takes place in the presence of an acid medium. The acid is drained from the reaction vessel at the rate of 15ml/s as a result of the density difference of the acid from the reacting component. To avoid wastage of acid, it is recycled to an acid tank which has 1000 L capacity. The acid drained from the reaction vessel, picks up 50 g/L solids from the reactor. Acid is fed once again to the process from acid tank. When the process is started, the acid is almost pure in the tank as a result of filtration. As the reaction proceeds, acid in the tank gets more and more contaminated with the solids. The concentration of the solids should not exceed 100 g/L from the process point of view. The batch time is 16h. Estimate whether the concentration of the solids will exceed 100g/L during the batch reaction.
The dissociation constant Kd for ligand binding to the receptor is 10-7 M. The concentration of ligand required for occupying 10% of receptors is
The affinity ligand is _________ in nature in the process of affinity ultrafiltration.
Which of the following chemicals are used to treat the instruments made out of polymers? i) Ethylene Oxide ii) Hydrochloric Acid iii) Silver Cyanide iv) Ozone v) Bleach vi) Saline Solution vii) Sulphuric Acid viii) Glutaraldehyde and Formaldehyde ix) Phthalaldehyde x) Hydrogen Peroxide xi) Nitric Acid xii) Peracetic Acid xiii) Silver xiv) Formic Acid xv) Citric Acid
Solution-1 containing 10% nitric acid and 20% acetic acid at the rate F combines with Solution-2 containing 20% nitric acid and 10% acetic acid at the rate D, the product formed contains 30% nitric acid and 20% acetic acid at the rate P, how many independent equations containing F, D, and P are possible?
Solution-1 containing 10% hydrochloric acid and 20% acetic acid at the rate F combines with Solution-2 containing 20% hydrochloric acid and 30% acetic acid at the rate D, the product formed contains 20% hydrochloric acid and 30% acetic acid at the rate P, how many independent equations containing F, D, and P are possible?
Which among the following is an example of a case where a non-related ligand activates the receptor other than the physiological ligand?
Which domain mediate the High-affinity binding of a lipophilic ligand?
Which among the following cell-surface receptors is a Ligand-gated ion channel?