Nuclear Receptor Ligands MCQ

Test your knowledge with important Nuclear Receptor Ligands MCQ and their applications. These MCQs are beneficial for competitive exams too. Explore 30+ more Nuclear Receptor Ligands MCQs on Bissoy. Bissoy App

• Which nuclear receptor is activated by oxysterol intermediates in cholesterol biosynthesis?
  ক

  Liver X receptor (LXR)

  খ

  Peroxisome proliferator-activated receptors (PPARs)

  গ

  Vitamin D receptor

  ঘ

  Retinoic acid receptors (RARs)
• Which Peroxisome proliferator-activated receptors (PPARs) is the target of thiazolidinedione (TZD) antidiabetic drugs?
  ক

  PPAR- Beta

  খ

  PPAR- Alpha

  গ

  PPAR- Omega

  ঘ

  PPAR- Gamma
• Where is PPAR-gamma primarily expressed in the human body?
  ক

  Liver

  খ

  Kidney

  গ

  Adipocytes

  ঘ

  Pancreas
• Which is the PPAR that is primarily expressed in the liver?
  ক

  PPAR-Beta

  খ

  PPAR-Alpha

  গ

  PPAR-Omega

  ঘ

  PPAR-Gamma
• Which among the following molecules can activate all the three PPAR subtypes?
  ক

  Cholesterol

  খ

  Carbohydrate

  গ

  Fatty Acids

  ঘ

  Proteins
• Which among the following constitute the best-defined subfamily of metabolite-sensing nuclear receptors?
  ক

  Retinoid X receptor (RXR)

  খ

  Peroxisome proliferator-activated receptors (PPARs)

  গ

  Vitamin D receptor

  ঘ

  Retinoic acid receptors (RARs)
• 9-cis-isomer is a ligand for which nuclear receptor?
  ক

  Retinoid X receptor (RXR)

  খ

  Retinoic acid receptors (RARs)

  গ

  Vitamin D receptor

  ঘ

  Vitamin A receptor
• Which among the following is a high affinity ligand for retinoic acid receptors (RARs)?
  ক

  9-cis-Retinoic acid

  খ

  25-hydroxyvitamin D

  গ

  Nuclear receptor 3C2 (NR3C2)

  ঘ

  All-trans-retinoic acid
• Which is the most potent natural ligand of the vitamin D receptor?
  ক

  1,25-dihydroxyvitamin D3

  খ

  25-hydroxyvitamin D

  গ

  9-cis-Retinoic acid

  ঘ

  Nuclear receptor 3C2 (NR3C2)
• Which are the two vitamins that act as ligands for nuclear receptors?
  ক

  Vitamin A and Vitamin K

  খ

  Vitamin A and Vitamin D

  গ

  Vitamin E and Vitamin C

  ঘ

  Vitamin A and Vitamin C
• The function of nuclear receptor ligands and their receptors is to translate cue environments into changes in gene expression.
  ক

  True

  খ

  False
• In the genome, no nuclear receptor ligands are specifically encoded.
  ক

  True

  খ

  False
• Which among the following is the hormone that mediate the signals of multiple hormones?
  ক

  1,25-(OH)2-Vitamin D3

  খ

  9-cis-Retinoic acid

  গ

  Nuclear receptor 3C2 (NR3C2)

  ঘ

  Aldosterone
• Which among the following are classic hormones that use nuclear receptor ligands?
  ক

  Fatty acids and oxysterols

  খ

  Thyroid hormone and steroid hormones

  গ

  9-cis-Retinoic acid

  ঘ

  Bile acids
• What is the advantage of having lipophilicity in the nuclear receptor ligands?
  ক

  Helps in absorption to GI tract

  খ

  Helps in absorption to the lymphatic duct

  গ

  Helps in absorption to the liver

  ঘ

  Helps in absorption to the trachea