Which Peroxisome proliferator-activated receptors (PPARs) is the target of thiazolidinedione (TZD) antidiabetic drugs?
Which Peroxisome proliferator-activated receptors (PPARs) is the target of thiazolidinedione (TZD) antidiabetic drugs? Correct Answer PPAR- Gamma
A new class of oral antidiabetic agents is Thiazolidinediones (TZDs). In Type 2 (noninsulin dependent) diabetic patients, they selectively enhance or partially mimic certain insulin acts, triggering a slowly generated antihyperglycemic impact. PPAR-Gamma seems to be the target of antidiabetic thiazolidinedione (TZD) drugs that enhance insulin sensitivity. These pharmaceutical agents bind to PPAR-Gamma with very minute affinity.