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The homology-based method makes predictions based on significant matches of the query sequence with sequences of known genes.

The homology-based method makes predictions based on significant matches of the query sequence with sequences of known genes. Correct Answer True

For instance, if a translated DNA sequence is found to be similar to a known protein or protein family from a database search, this can be strong evidence that the region codes for a protein. Alternatively, when possible exons of a genomic DNA region match a sequenced cDNA, this also provides experimental evidence for the existence of a coding region.

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