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In protein/domain analysis, each protein in the predicted proteome is again used as a query of a curated protein sequence database such as ____ in order to locate similar domains and sequences. To find orthologs, very low E value scores (E<10<20) for the alignment score and an alignment that includes 60–80% of the query sequence are generally required in order to avoid matches to paralogs.

In protein/domain analysis, each protein in the predicted proteome is again used as a query of a curated protein sequence database such as ____ in order to locate similar domains and sequences. To find orthologs, very low E value scores (E<10<20) for the alignment score and an alignment that includes 60–80% of the query sequence are generally required in order to avoid matches to paralogs. Correct Answer SwissProt

The domain composition of each protein is also determined by searching for matches in domain databases such as Interpro. The analysis reveals how many domains and domain combinations are present in the proteome, and reveals any unusual representation that might have biological significance. The number of expressed genes in each family can also be compared to the number in other organisms to determine whether or not there has been an expansion of the family in the genome.

Related Questions

An all-against-all analysis requires first making a database of the proteome. This database is then sequentially searched by each individual protein sequence of the proteome using a rapid database similarity search tool such as _______
What is the result of segmenting a network with a bridge (switch)?
1. It increases the number of collision domains.
2. It decreases the number of collision domains.
3. It increases the number of broadcast domains.
4. It decreases the number of broadcast domains.
5. It makes smaller collision domains.
6. It makes larger collision domains.
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Who suggested that the global alignment scores between unrelated protein sequences followed the extreme value distribution, similar to local alignment scores? And when?
Which of the following are benefits of VLANs?
1. They increase the size of collision domains.
2. They allow logical grouping of users by function.
3. They can enhance network security.
4. They increase the size of broadcast domains while decreasing the number of collision domains.
5. They simplify switch administration.
6. They increase the number of broadcast domains while decreasing the size of the broadcast domains.