Bissoy.com
Doctors Medicines MCQs Q&A

Who suggested that the global alignment scores between unrelated protein sequences followed the extreme value distribution, similar to local alignment scores? And when?

Who suggested that the global alignment scores between unrelated protein sequences followed the extreme value distribution, similar to local alignment scores? And when? Correct Answer Abagyan and Batalov, in 1997

Abagyan and Batalov, in 1997, suggested the above observation. However, since the scoring system that they used favored local alignments, these alignments they produced may not be global but local. Unfortunately, there is no equivalent theory on which to base an analysis of global alignment scores as there is for local alignment scores.

Related Questions

In protein/domain analysis, each protein in the predicted proteome is again used as a query of a curated protein sequence database such as ____ in order to locate similar domains and sequences. To find orthologs, very low E value scores (E<10<20) for the alignment score and an alignment that includes 60–80% of the query sequence are generally required in order to avoid matches to paralogs.
In an entrance exam, 7 candidates participated - Neeraj, Kalash, Bharat, Saurav, Tarun, Mohan, and Varun 1. No students get the same scores. 2. Varun always scores more than Neeraj 3. Neeraj always scores more than Kalash. 4. Each time either Bharat scores the highest and Tarun gets the least, or alternatively Saurav scores the highest and Mohan or Kalash scores the least. If Saurav is ranked sixth and Kalash is ranked fifth, which of the following is CORRECT?
Seven students A, B, C, D, E, F and G take a series of test. No two students get the same marks. A always scores more than B. G always scores more than A. Each time either C scores the highest and E scores the least or D scores the highest and F or B scores the least. If D is ranked sixth and B is ranked fifth according to their marks, then which of the following can be true?
Read the following information and answer the questions giver below it: *Seven students P,Q,R,S,T,U and V take a series of tests. *No two students get similar marks. *V always scores more than P. *P always scores more than Q. *Each time either R scores the highest and T gets the lest, or alternatively S scores the highest and U or Q scores the least. If S is ranked sixth and Q is ranked fifth, which of the following can be true ?
Read the following information and answer the questions giver below it: *Seven students P,Q,R,S,T,U and V take a series of tests. *No two students get similar marks. *V always scores more than P. *P always scores more than Q. *Each time either R scores the highest and T gets the lest, or alternatively S scores the highest and U or Q scores the least. If R is ranked second and Q is ranked fifth, which of the following must be true ?
Read the following information and answer the questions giver below it: *Seven students P,Q,R,S,T,U and V take a series of tests. *No two students get similar marks. *V always scores more than P. *P always scores more than Q. *Each time either R scores the highest and T gets the lest, or alternatively S scores the highest and U or Q scores the least. If R gets most, V should be ranked not lower than--
Read the following information and answer the questions giver below it: *Seven students P,Q,R,S,T,U and V take a series of tests. *No two students get similar marks. *V always scores more than P. *P always scores more than Q. *Each time either R scores the highest and T gets the lest, or alternatively S scores the highest and U or Q scores the least. If S is ranked second, which of the following can be true ?
The resulting tree is then used to guide the alignment of the most closely related sequences and groups of sequences. The resulting alignment is a global alignment produced by the Needleman-Wunsch algorithm.
On analysis of the alignment scores of random sequences will reveal that the scores follow a different distribution than the normal distribution called the _________
When random or unrelated sequences are compared using a global alignment method, they can have ____________ reflecting the tendency of the global algorithm to match as many characters as possible.