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Threading or structural fold recognition predicts the structural fold of an unknown protein sequence by fitting the sequence into a structural database and selecting the best-fitting fold.

Threading or structural fold recognition predicts the structural fold of an unknown protein sequence by fitting the sequence into a structural database and selecting the best-fitting fold. Correct Answer True

To determine whether a protein sequence adopts a known three-dimensional structure fold relies on threading and fold recognition methods. The comparison emphasizes matching of secondary structures, which are most evolutionarily conserved. Therefore, this approach can identify structurally similar proteins even without detectable sequence similarity.

Related Questions

Protein A will fold into its native state only when protein B is also present in the solution. However, protein B can fold itself into native confirmation without the presence of protein A. Which of the following is true?
In the pairwise energy based method, a protein sequence is searched for in a structural fold database to find the best matching structural fold using ______ criteria.
Because threading and fold recognition detect structural homologs ________ relying on sequence similarities, they have been shown to be _______ than PSI-BLAST in finding distant evolutionary relationships
The predicate in a where clause can involve Boolean operations such as and. The result of true and unknown is_______ false and unknown is _____ while unknown and unknown is _____
You are the administrator of a SQL Server 2000 computer. The server contains a database named FinanceData that is used by a client/server application. Each employee has a SQL Server login that the application uses to access the server.Your company hires a new employee named Andrew. You create a SQL Server login named Andrew. You also create a database user named Andrew in the database and grant the database user full permissions in the database.Whenever Andrew runs the client/server application, he receives the following error message: "Invalid object name." Andrew also reports that he cannot access the database by using the application.You need to ensure that Andrew can use the application. Which Transact-SQL statement should you execute?
Phytase, an enzyme produced by Aspergillus niger can be adsorbed on microcrystalline cellulose powder (MCCP). The adsorption follows a Langmuir isotherm and the maximum concentration of the protein that can be obtained on the adsorbent is 70 mg cm-1. At a concentration of 50 mg L-1 of protein in the solution, the concentration of protein on the adsorbent reaches 35 mg cm-1. It is desired to recover 90% of the protein from 1.5 liter of the cell free culture filtrate containing 220 mg L-1 protein by addition of MCCP to the solution. The concentration of the protein adsorbed on the solid at equilibrium will be:
Which of the following is untrue about threading and fold recognition?
In protein/domain analysis, each protein in the predicted proteome is again used as a query of a curated protein sequence database such as ____ in order to locate similar domains and sequences. To find orthologs, very low E value scores (E<10<20) for the alignment score and an alignment that includes 60–80% of the query sequence are generally required in order to avoid matches to paralogs.
Directions : In each of the following questions a statement is given, followed by two conclusions. Give answer :

Statements : About 50 per cent of the animal by-products - hair, skin, horns etc. is edible protein. American chemists have developed a method of isolating 45 per cent of this protein. They used an enzyme developed in Japan to break down soya protein.

Conclusions :
I. Americans have not been able to develop enzymes.
II. Animal by-products protein has the same composition as soya protein.
A source of unknown frequency gives 4 beats / s, when sounded with a source of known frequency 250 Hz. The second harmonic of the source of unknown frequency gives five beats per second, when sounded with a source of frequency 513 Hz. The unknown frequency is: