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Which of the following is untrue about threading and fold recognition?

Which of the following is untrue about threading and fold recognition? Correct Answer If the protein fold to be predicted does not exist in the fold library, the method won’t necessarily fail

A disadvantage compared to homology modeling lies in the fact that threading and fold recognition do not generate fully refined atomic models for the query sequences. This is because accurate alignment between distant homologs is difficult to achieve. Instead, threading and fold recognition procedures only provide a rough approximation of the overall topology of the native structure.

Related Questions

Threading or structural fold recognition predicts the structural fold of an unknown protein sequence by fitting the sequence into a structural database and selecting the best-fitting fold.
Because threading and fold recognition detect structural homologs ________ relying on sequence similarities, they have been shown to be _______ than PSI-BLAST in finding distant evolutionary relationships
Which of the following can be one of the steps in stacking?
1. Divide the training data into k folds
2. Train k models on each k-1 folds and get the out of fold predictions for remaining one fold
3. Divide the test data set in "k" folds and get individual fold predictions by different algorithms
Consider the following statements about folds: An anticline is a fold that is convex upward, and a syncline is a fold that is concave upward. An anticlinorium is a large syncline on which minor folds are superimposed, and a synclinorium is a large anticline on which minor folds are superimposed. Which of the above statements is correct?
How did Britain secure a title to rule India? Consider the following statements and select the correct code: (a) The dissolution of the Mughal empire and the cessions by and the conquests from the Marathas, the Sikhs and other territorial sovereigns from 1757 till 1857. (b) Sovereignty in India involved, under the British Constitutional Law and under the 'Law of Nations' as expounded in Europe, the authority of British parliament and the recognition of all civilized nations. (c) The grant of charter carried sovereign status to the East India Company, and the treaties to Paris and Versailles and Congress of Vienna conveyed international recognition to this status. (d) After the suppression of the Revolt of 1857, Mughal Emperor transferred the sovereignty to Britain
Protein A will fold into its native state only when protein B is also present in the solution. However, protein B can fold itself into native confirmation without the presence of protein A. Which of the following is true?
When axial plane of a fold is vertical and either of the limbs have the same amount of dip then such fold is described as
The type of fold in which fold angle is between 10° to 90°?
A fold in which the folding continues in the direction of the axis of the fold is ___________
In the pairwise energy based method, a protein sequence is searched for in a structural fold database to find the best matching structural fold using ______ criteria.