Clearance of a drug

A Is reduced when the drug is strongly protein bound
B Represents the volume of blood from which the drug is completely eliminated in unit time
C Is increased in hepatic failure
D Is not dependent on renal function
E Cannot exceed glomerular filtration rate

Correct Answer: Is reduced when the drug is strongly protein bound, Represents the volume of blood from which the drug is completely eliminated in unit time

Bissoy MCQ
#MS #Pharmacology #General pharmacology #Drug clearance

Related Questions

A drug that is highly effective in treating many types of infection can,at present,be obtained only from the bark of the ibora , a tree that is quite rare in the wild. It takes the bark of 5000 trees to make one kilogram of the drug. It follows, therefore, that continued production of the drug must inevitably lead to the ibore's extinction. Which of the following,if true, most seriously weakens the arguments above ?
A The drug made from the ibora bark is dispensed to doctors from a central authority
B The drug made from the ibora bark is expensive to produce
C The leaves of the ibora are used in a number of medical products
D The ibora can be propagated from cuttings and grown under cultivation
There is always some steam left in the clearance space from the previous stroke. This steam left in the clearance space is called
A Wet steam
B Saturated steam
C Superheated steam
D Cushion steam
Bioavailability of a drug may be decreased if the drug is
A Water soluble
B Protein in nature
C Ionized
D Acid stable
E Lipid soluble
Following subcutaneous injection of a drug into a healthy young adult, dilatation of the pupil and a rise in systolic blood pressure are produced. The drug could be
A Acting by stimulating  and  receptors
B Acting by blocking sympathetic ganglia
C Atropine
D Adrenaline
E Morphine
Plasma clearance value of glucose is :
A 125ml /min
B 140ml/min
C 0ml / min
D 75ml / min
Big Shop Ltd. set up a cold storage in Rajshahi for preserving agricultural products, but so far the company _____the clearance from the Agriculture Ministry.
A will take
B never takes
C has not taken
D would not take
The renal clearance of
A PAH is a measure of renal plasma flow
B Phosphate is decreased by parathromone
C Protein is normally zero
D Bicarbonate is similar to that of glucose
E Creatinine provides an estimate of renal plasma flow
The renal plasma clearance value of a substance is
A Directly related to the rate of urine formation
B Expressed in units of volume per unit time
C Inversely related to its urinary concentration
D Directly related to its plasma concentration
E The volume of urine that contains the amount of the substance
The net work input required for compressor with increase in clearance volume
A Increases
B Decreases
C Remains same
D Increases/decreases depending on compressor capacity
Volumetric efficiency of a compressor without clearance volume
A Increases with increase in compression ratio
B Decreases with increase in compression ratio
C Is not dependent upon compression ratio
D May increase/decrease depending on compressor capacity

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