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Regarding autosomal dominant inheritance
A Risk remain same for each successive pregnancy
B Heterozygotes are phenotypically affected
C High new mutation rate
D 25% of children are affected
E Both sex are not equally affected
Autosomal dominant inheritance is characterized by
A Variable expression of disorders
B Equal male-female involvement
C Early onset
D Complete penetrance
E Transmission only by females
Autosomal dominant mode of transmission occurs in
A Hereditary spherocytosis
B Marfan’s syndrome
C Huntington’s disease
D Phenylketonuria
E Cystic fibrosis
In country A, the first 1,000 dollar of any inheritance are untaxed. After the first 1,000 dollar, inheritances are taxed at rate of 65%. How large must an inheritance be, to the nearest dollar, in order to amount to 2,500 dollar after the inheritance tax?
A 7,143
B 5,286
C 4,475
D 3,475
Following are the autosomal dominant disorders
A Neurofibromatosis
B Marfan’s syndrome
C Wilson disease
D Duchene muscular dystrophy
E Hemophilia
An autosomal dominant trait has the following features
A Normal child is possible even if both of the parents are affected
B That trait is seen in every generation
C New mutation is suspected if the parents are genetically normal
D Male are more affected than female
E Most of the diseases are due to enzyme defect
An autosomal dominant trait usually has the following features
A At least one of the parents show the trait
B Both sexes are equally affected
C Trait shows complete penetrance
D More often the gene codes an enzyme
E Carriers have normal phenotype
The following are autosomal dominant disorders
A Neurofibromatosis
B Polycystic kidney disease
C Achondroplasia
D Diabetes insipidus
E Congenital adrenal hyperplasia
Characteristics of autosomal dominant disorders
A Transmitted in a vertical pattern
B New mutation may occur
C Skipped generation is not observed
D Consanguity between parents present
E 50% chance of carrier in offspring
Autosomal dominant diseases are
A Achondroplasia
B Neurofibromatosis
C Cystic fibrosis
D Phenylketonuria
E Tay-sacs disease

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