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Regarding autosomal dominant inheritance
A Risk remain same for each successive pregnancy
B Heterozygotes are phenotypically affected
C High new mutation rate
D 25% of children are affected
E Both sex are not equally affected
Mode of inheritance is autosomal dominant in the following conditions
A Neurofibromatosis
B Tuberous sclerosis
C Thalassaemia
D Phenylketonuria
E Hemophilia
In country A, the first 1,000 dollar of any inheritance are untaxed. After the first 1,000 dollar, inheritances are taxed at rate of 65%. How large must an inheritance be, to the nearest dollar, in order to amount to 2,500 dollar after the inheritance tax?
A 7,143
B 5,286
C 4,475
D 3,475
Characteristics of autosomal dominant disorders
A Transmitted in a vertical pattern
B New mutation may occur
C Skipped generation is not observed
D Consanguity between parents present
E 50% chance of carrier in offspring
Autosomal dominant diseases are
A Achondroplasia
B Neurofibromatosis
C Cystic fibrosis
D Phenylketonuria
E Tay-sacs disease
Examples of autosomal dominant disorders are
A Neurofibromatosis
B Familial polyposis coli
C Marfan syndrome
D Fragile X syndrome
E Ducchene muscular dystrophy
Following are the autosomal dominant disorders
A Neurofibromatosis
B Marfan’s syndrome
C Wilson disease
D Duchene muscular dystrophy
E Hemophilia
Features of autosomal dominant disorders are
A Manifested in heterozygous state
B Both males and females are affected
C New mutations occur in germ cells of elderly father
D Complete penetrance is common
E Onset is in early life
Autosomal dominant disorders are
A Huntington's disease
B Marfan syndrome
C Polydactyly
D Cystic fibrosis
E Sickle cell anemia
Autosomal dominant mode of transmission occurs in
A Hereditary spherocytosis
B Marfan’s syndrome
C Huntington’s disease
D Phenylketonuria
E Cystic fibrosis

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