In DNA and RNA nitrogen is present in the ring system. Can Kjeldahl method can be used for the estimation of nitrogen present in these?give reasons.

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In DNA and RNA nitrogen is present in heterocyclic rings. Kjeldahl method can not be used to estimate nitrogen present in the ring because cannot be completely converted in to (NH4)2SO4 during digestion. Therefore Kjeldahl method cannot be used to estimate nitrogen present in DNA and RNA.

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