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In chemistry, the Möbius–Hückel treatment is a methodology used to predict whether a reaction is allowed or forbidden. It is often used alone with the Woodward–Hoffmann approach. The description in this article uses the plus-minus sign notation for parity as shorthand while proceeding around a cycle of orbitals in a molecule or system, while the Woodward–Hoffmann methodology uses a large number of rules with the same consequences.

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