Widespread resistance of the malarial parasites to drugs like chloroquine has prompted attempts to develop a malarial vaccine to combat malaria. Why is it difficult to develop an effective malaria vaccine?

Widespread resistance of the malarial parasites to drugs like chloroquine has prompted attempts to develop a malarial vaccine to combat malaria. Why is it difficult to develop an effective malaria vaccine? Correct Answer Man does not develop immunity to malaria during natural infection

The correct answer is Man does not develop immunity to malaria during natural infection.

 Key Points

  • It is difficult to develop an effective malaria vaccine because repeated natural infection does not produce detectable resistance to the exo-erythrocytic cycle of malaria in man.

 Important Points

  • Malaria is typically transmitted through the bite of an infected Anopheles mosquito.
  • Infected mosquitoes carry the Plasmodium parasite.
  • When this mosquito bites, the parasite is released into the bloodstream.
  • Different species of Plasmodium (P. vivax, P. malaria, and P. falciparum) are responsible for different types of malaria.
  • Of these, malignant malaria caused by Plasmodium falciparum is the most serious one and can even be fatal.

 Additional Information

  • World Malaria Day is celebrated on April 25 by the World Health Organisation and several other international organizations.

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