Which is the endogenous ligand for the orphan G protein–coupled receptor APJ?

Which is the endogenous ligand for the orphan G protein–coupled receptor APJ? Correct Answer Apelin

Apelin is a 36-amino acid peptide originally isolated from bovine stomach extracts that has been determined to be the orphan G protein-coupled APJ receptor endogenous ligand (now designated APLNR). In peripheral tissues, such as the lung, heart, and mammary gland, apelin and its receptor are commonly expressed, with apelin most abundant in the stomach.
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