To which enzymes does the members of the cytokine family of receptors bind to exhibit the enzyme activity?
To which enzymes does the members of the cytokine family of receptors bind to exhibit the enzyme activity? Correct Answer Janus family of tyrosine kinases
Members of the receptor cytokine family do not themselves exhibit enzymatic action. Instead, they bind members in a proline-rich region of the Janus family of tyrosine kinases (JAKs). Janus Kinases (JAKs) are enzymes that phosphorylate residues of tyrosine on target proteins that primarily function as a signal transducer in the signalling pathway of JAK-STAT.