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Cytotoxic T-lymphocyte-associated antigen 4 is expressed by activated effector T cells and it represses the proliferation of T cell.

Cytotoxic T-lymphocyte-associated antigen 4 is expressed by activated effector T cells and it represses the proliferation of T cell. Correct Answer True

Cytotoxic T-lymphocyte-associated antigen 4 is also denoted as CTLA-4. It is a glycoprotein expressed by activated effector T cells. It plays a major role in repression of T cell proliferation and helps in enhancing the progressive ability of cell cycle. CTLA-4 also has some inhibitory functions which might produce irregular functioning of T cells. The most important clinical use of CTLA-4 is that it is targeted by antibodies therapeutically in human malignancies in order to block its inhibitory effects.

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