Cytotoxic T-cells MCQ

Test your knowledge with important Cytotoxic T-cells MCQ and their applications. These MCQs are beneficial for competitive exams too. Explore 30 + more Cytotoxic T-cells MCQs at Bissoy

• Which cytotoxic T lymphocyte(s) have become important considerations in the design of cancer vaccine-based clinical trials?
  ক

  MHC-restricted CD8+ and CD4+ CTLs

  খ

  MHC-restricted CD8+ CTLs

  গ

  MHC-restricted CD4+ CTLs

  ঘ

  MHC-linked CD8+ and CD4+ CTLs
• Which of the following cytokine is not released by Cytotoxic CD8+ T cells in order to carry out host defence mechanisms?
  ক

  IFN-γ

  খ

  TNF-α

  গ

  TGF-β

  ঘ

  TNF-β
• Cytotoxic T cells play an important role in pathogenesis of which autoimmune disease?
  ক

  Diabetes melitus

  খ

  Vitiligo

  গ

  Systemic sclerosis

  ঘ

  Paraneoplastic pemphigus
• Cytotoxic T cells kill target cells by interaction of which two cytokines?
  ক

  IFN-γ and TNF-α

  খ

  IFN- and IL-1

  গ

  TNF-α and IL-2

  ঘ

  IL-13 and IL-2
• Who demonstrated priming of Cytotoxic T lymphocytes responses against tumour antigen?
  ক

  Edward Jenner

  খ

  Ernst Haeckel

  গ

  Paul Ehrlich

  ঘ

  Schoenberger
• Cytotoxic T-lymphocyte-associated antigen 4 is expressed by activated effector T cells and it represses the proliferation of T cell.
  ক

  True

  খ

  False
• Which cell works as a dual receptor in CTLs?
  ক

  CD4

  খ

  CD8

  গ

  CD13

  ঘ

  CD4+
• Which of the following is NOT a sequential signal for the generation of effector Cytotoxic T lymphocytes?
  ক

  TCR ligation

  খ

  Transmission of co-stimulatory signals

  গ

  IL-2 mediated signalling

  ঘ

  Internalization of TCR
• Secretion of exosomes by fully activated Cytotoxic T cells is mediated by which cytokine?
  ক

  IL-15

  খ

  IL-12

  গ

  IL-2

  ঘ

  IL-5
• Which cells produce cytokines to trigger Cytotoxic T lymphocytes (CTLs)?
  ক

  CD4+

  খ

  CD8+

  গ

  CD28+

  ঘ

  CD69+