Immunoglobulin class switching within intestine may be directed towards which of the following antibody isotype other than IgA?
Immunoglobulin class switching within intestine may be directed towards which of the following antibody isotype other than IgA? Correct Answer IgG and IgE
Immunoglobulin class-switch mechanism that takes place within the intestine is associated and directed towards IgA. However, in the presence of certain cytokines, isotype IgA is forced to shift toward IgG or IgE. In such cases, high inflammation occurs due to which TH1 and TH2 cytokines control the commitment of naïve B cells towards IgE and IgG. This results in production of plasma cells.
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Feb 20, 2025