Where does the variable region rearrangements of an immunoglobulin take place?

Where does the variable region rearrangements of an immunoglobulin take place? Correct Answer Bone marrow

During the process of B cell maturation, the variable region rearrangements of an immunoglobulin take place. The whole process is carried out in bone marrow.

Related Questions

Determine the correctness or otherwise of the following Assertion (A) and Reason (R).
Assertion: An antigen recognized by one immunoglobulin subtype is not recognized by any other subtype.
Reason: Immunoglobulin subtypes differ from each other both in the variable and in the constant regions.