Because of which interaction from the following does the costimulatory signal arises?

Because of which interaction from the following does the costimulatory signal arises? Correct Answer B7 and CD28

The costimulatory signal comes from the interaction between B7 and CD28. This particular signal is important for various reasons. It is necessary for full activation of B cells and helps in preventing apoptosis, in regulation of proliferation and differentiation and also for cell to cell cooperation.
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