The cysteine residues present in the reduced form in peptides that enter the endoplasmic reticulum lumen are converted into ____________ when they leave the compartment.
The cysteine residues present in the reduced form in peptides that enter the endoplasmic reticulum lumen are converted into ____________ when they leave the compartment. Correct Answer disulfide bonds
Disulfide bonds play an important role in the stability of proteins. When the proteins enter ER lumen they contain cysteine residues in the reduced form (-SH) which is converted to oxidized disulfide bonds (-SS-) when they leave the ER, a reaction catalyzed by protein disulfide isomerase (PDI).
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Feb 20, 2025