Which alternate form of histone is seen in centromeric histones of humans?
Which alternate form of histone is seen in centromeric histones of humans? Correct Answer CENP-A
It has been observed that the human chromatin near the centromere has a unique structure. In particular, histone H3 is replaced by its variant CENP-A. CENP-A is uniformly present in centromere of all organisms that have been studied and thus are thought to be of prime requisite for the assembly of the kinetochore proteins needed for centromere function.