Nucleosome was first described in 1974 by ___________

Nucleosome was first described in 1974 by ___________ Correct Answer Roger Kornberg

The basic structural unit of chromatin, the nucleosome, was described by Roger Kornberg in 1974. Two types of experiments led to Kornberg’s proposal of the nucleosome model. First, partial digestion of chromatin with micrococcal nuclease was found to yield DNA fragments approximately 200 bp long. In contrast, similar digestion of naked DNA yielded a continuous smear of randomly sized fragments.
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