Nucleophilic substitution reaction of pyridine is most effective in which of the conditions?

Nucleophilic substitution reaction of pyridine is most effective in which of the conditions? Correct Answer No specific condition requirements

The nitrogen atom makes pyridines more reactive towards nucleophilic substitution, particularly at the 2- and 4-positions, by lowering the LUMO energy of the π system of pyridine.

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