Each genome sequence is scanned for protein-encoding genes using gene models trained on known gene sequences from the same organism.
Each genome sequence is scanned for protein-encoding genes using gene models trained on known gene sequences from the same organism. Correct Answer True
For a new genome, each predicted gene is translated into a protein sequence; the collection of protein sequences encoded by the genome is the proteome of the organism. every protein in the proteome is then used as a query sequence in a database similarity search. Matching database sequences are realigned with the query sequence to evaluate the extent and significance of the alignment.
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Feb 20, 2025