Consider the following statements regarding Genome Sequencing: 1. Genome sequencing is figuring out the order of DNA nucleotides, or bases, in a genome—the order of Adenine, Cytosine, Guanines, and Thymine that make up an organism's DNA. 2. Human genome is made up of 46 chromosome pairs with a total of about 3 billion DNA base pairs. 3. There are 24 distinct human chromosomes: 22 autosomal chromosomes, plus the sex-determining X and Y chromosomes. Which of the statements given above is/are correct?
Consider the following statements regarding Genome Sequencing: 1. Genome sequencing is figuring out the order of DNA nucleotides, or bases, in a genome—the order of Adenine, Cytosine, Guanines, and Thymine that make up an organism's DNA. 2. Human genome is made up of 46 chromosome pairs with a total of about 3 billion DNA base pairs. 3. There are 24 distinct human chromosomes: 22 autosomal chromosomes, plus the sex-determining X and Y chromosomes. Which of the statements given above is/are correct? Correct Answer 1 and 3 only
The correct answer 1 and 3 only.
Key Points
- Genome Sequencing
- Genome sequencing is figuring out the order of DNA nucleotides, or bases, in a genome—the order of Adenine, Cytosine, Guanines, and Thymine that make up an organism's DNA.
- Hence statement 1 is correct.
- Human genome
- It is made up of 23 chromosome pairs with a total of about 3 billion DNA base pairs. Hence statement 2 is not correct.
- There are 24 distinct human chromosomes: 22 autosomal chromosomes, plus the sex-determining X and Y chromosomes. Hence statement 3 is correct.
- Chromosomes 1-22 are numbered roughly in order of decreasing size.
- Somatic cells usually have one copy of chromosomes 1-22 from each parent, plus an X chromosome from the mother and either an X or Y chromosome from the father, for a total of 46.
- There are an estimated 20,000-25,000 human protein-coding genes.
- Genome sequencing is figuring out the order of DNA nucleotides, or bases, in a genome—the order of Adenine, Cytosine, Guanines, and Thymine that make up an organism's DNA.
Important Points
- Genome Mapping
- It describes the methods used to identify the locus of a gene and the distances between genes.
- Gene mapping can also describe the distances between different sites within a gene.
- Taking inspiration from the Human Genome Project, the Department of Biotechnology (DBT) initiated the ambitious “Genome India Project” (GIP) in January 2020.
- The GIP aims to collect 10,000 genetic samples from citizens across India, to build a reference genome.
- It describes the methods used to identify the locus of a gene and the distances between genes.
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Feb 20, 2025