It is important to use bioinformatics tools to predict sites for posttranslational modifications based on specific protein sequences. However, prediction of such modifications can often be difficult because the short lengths of the sequence motifs associated with certain modifications.
It is important to use bioinformatics tools to predict sites for posttranslational modifications based on specific protein sequences. However, prediction of such modifications can often be difficult because the short lengths of the sequence motifs associated with certain modifications. Correct Answer True
This often leads to many false-positive identifications. One such example is the known consensus motif for protein phosphorylation, -x-. Such a short motif can be found multiple times in almost every protein sequence. Most of the predictions based on this sequence motif alone are likely to be wrong, producing very high rates of false-positives.
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Feb 20, 2025