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If the centroid structure is different from the minimum free-energy structure, the centroid structure is often closer to the phylogenetic prediction and contains fewer base pairs, or fewer false-positive base pair predictions, than the minimum free-energy prediction.

If the centroid structure is different from the minimum free-energy structure, the centroid structure is often closer to the phylogenetic prediction and contains fewer base pairs, or fewer false-positive base pair predictions, than the minimum free-energy prediction. Correct Answer True

The point is to show a structure that represents a group of structures rather than a single predicted structure. Many long RNA sequences, such as viral genomes or mRNA, may not have a single structure but instead have a dynamic structure that has some conserved features but also varies and changes, and these many conformations may all exist simultaneously in the cell.

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