Energy minimization has to be used with caution because excessive energy minimization often moves residues away from their correct positions.
Energy minimization has to be used with caution because excessive energy minimization often moves residues away from their correct positions. Correct Answer True
Only limited energy minimization is recommended (a few hundred iterations) to remove major errors, such as short bond distances and close atomic clashes. Key conserved residues and those involved in cofactor binding have to be restrained if necessary during the process.
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Feb 20, 2025