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Profiles are found by performing the _____ MSA of a group of sequences and then removing the _______ regions in the alignment into a smaller MSA.

Profiles are found by performing the _____ MSA of a group of sequences and then removing the _______ regions in the alignment into a smaller MSA. Correct Answer global, more highly conserved

Profiles are found by performing the global MSA of a group of sequences and then removing the more highly conserved regions in the alignment into a smaller MSA. A scoring matrix for the MSA, called a profile, is then made. The profile is composed of columns much like a mini-MSA and may include matches, mismatches, insertions, and deletions.

Related Questions

Progressive alignment methods use the dynamic programming method to build an MSA starting with the most related sequences and then progressively adding less related sequences or groups of sequences to the initial alignment.
In the method of extraction of blocks from a global or local MSA, a global MSA of related protein sequences usually includes regions that have been aligned without gaps in any of the sequences.
The resulting tree is then used to guide the alignment of the most closely related sequences and groups of sequences. The resulting alignment is a global alignment produced by the Needleman-Wunsch algorithm.
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