The global sequence alignment is suitable when the two sequences are of dissimilar length, with a negligible degree of similarity throughout.

The global sequence alignment is suitable when the two sequences are of dissimilar length, with a negligible degree of similarity throughout. Correct Answer False

The global sequence alignment is suitable when the two sequences are of similar length, with a significant degree of similarity throughout. It gives the best alignment over the entire length of two sequences.
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Related Questions

Let D be a simple graph on 10 vertices such that there is a vertex of degree 1, a vertex of degree 2, a vertex of degree 3, a vertex of degree 4, a vertex of degree 5, a vertex of degree 6, a vertex of degree 7, a vertex of degree 8 and a vertex of degree 9. What can be the degree of the last vertex?
If the two sequences share significant similarity, it is extremely ______ that the extensive similarity between the two sequences has been acquired randomly, meaning that the two sequences must have derived from a common evolutionary origin.
The resulting tree is then used to guide the alignment of the most closely related sequences and groups of sequences. The resulting alignment is a global alignment produced by the Needleman-Wunsch algorithm.
Progressive alignment methods use the dynamic programming method to build an MSA starting with the most related sequences and then progressively adding less related sequences or groups of sequences to the initial alignment.
Which of the following statements are CORRECT when a protein sequence database is searched using the BLAST algorithm?
P. A larger E-value indicates higher sequence similarity.
Q. E-value -10 indicates sequence homology.
R. A higher BLAST score indicates higher sequence similarity.
S. E-value > 10-10 indicates sequence homology.
Sequence similarity and sequence identity are synonymous for nucleotide sequences and protein sequences as well.
The degree of sequence variation in the alignment reveals evolutionary relatedness of different sequences, whereas the conservation between sequences reflects the changes that have occurred during evolution in the form of substitutions, insertions, and deletions.
In protein/domain analysis, each protein in the predicted proteome is again used as a query of a curated protein sequence database such as ____ in order to locate similar domains and sequences. To find orthologs, very low E value scores (E<10<20) for the alignment score and an alignment that includes 60–80% of the query sequence are generally required in order to avoid matches to paralogs.
In sequence alignment by BLAST, each word from query sequence is typically _______ residues for protein sequences and _______ residues for DNA sequences.
A copper steel rod (k = 55 W/m degree) has been attached to a plane wall which is maintained at a temperature of 350 degree Celsius. The rod is 8 cm long and has the cross-section of an equilateral triangle with each side 5 mm. Determine the heat dissipation from the rod if it is exposed to a convection environment at 25 degree Celsius with unit surface conductance 100 W/m2 degree. Consider end surface loss to be negligible