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Sequence similarity and sequence identity are synonymous for nucleotide sequences and protein sequences as well.

Sequence similarity and sequence identity are synonymous for nucleotide sequences and protein sequences as well. Correct Answer False

Sequence similarity and sequence identity are synonymous for nucleotide sequences. For protein sequences, however, the two concepts are very different. In a protein sequence alignment, sequence identity refers to the percentage of matches of the same amino acid residues between two aligned sequences. Similarity refers to the percentage of aligned residues that have similar physicochemical characteristics and can be more readily substituted for each other.

Related Questions

Which of the following statements are CORRECT when a protein sequence database is searched using the BLAST algorithm?
P. A larger E-value indicates higher sequence similarity.
Q. E-value -10 indicates sequence homology.
R. A higher BLAST score indicates higher sequence similarity.
S. E-value > 10-10 indicates sequence homology.
If the two sequences share significant similarity, it is extremely ______ that the extensive similarity between the two sequences has been acquired randomly, meaning that the two sequences must have derived from a common evolutionary origin.
Phytase, an enzyme produced by Aspergillus niger can be adsorbed on microcrystalline cellulose powder (MCCP). The adsorption follows a Langmuir isotherm and the maximum concentration of the protein that can be obtained on the adsorbent is 70 mg cm-1. At a concentration of 50 mg L-1 of protein in the solution, the concentration of protein on the adsorbent reaches 35 mg cm-1. It is desired to recover 90% of the protein from 1.5 liter of the cell free culture filtrate containing 220 mg L-1 protein by addition of MCCP to the solution. The concentration of the protein adsorbed on the solid at equilibrium will be:
The translated sequence can then be compared to a database of protein sequences with the hope of finding a strong similarity to a protein of known function, and hence to identify the function of the cloned EST.
For studying the evolution of ________ divergent groups of organisms, one may choose either ______ nucleotide sequences, such as ribosomal RNA or protein sequences.
In protein/domain analysis, each protein in the predicted proteome is again used as a query of a curated protein sequence database such as ____ in order to locate similar domains and sequences. To find orthologs, very low E value scores (E<10<20) for the alignment score and an alignment that includes 60–80% of the query sequence are generally required in order to avoid matches to paralogs.
Which one of the following tools is used to compare all the possible six-open reading frames of a given nucleotide query sequence with all the available six-open reading frames of the nucleotide sequence database?
Directions : In each of the following questions a statement is given, followed by two conclusions. Give answer :

Statements : About 50 per cent of the animal by-products - hair, skin, horns etc. is edible protein. American chemists have developed a method of isolating 45 per cent of this protein. They used an enzyme developed in Japan to break down soya protein.

Conclusions :
I. Americans have not been able to develop enzymes.
II. Animal by-products protein has the same composition as soya protein.
In sequence alignment by BLAST, each word from query sequence is typically _______ residues for protein sequences and _______ residues for DNA sequences.
Given below are six sentences. A and F are the first and the last sentences. The rest of the sentences namely B, C, D and E are jumbled. Select the option that gives their correct order. A. The well was highly useful to the people who lived in the surrounding huts. B. The well was dangerous: but it had been there for so long that no one worried about it. C. Consequently, the mouth of the well had gradually widened as the soil and rocks on the side fell in. D. There had never been any money for a wall around the well. E. They had dug it two years before because the only water tap in the colony was not enough for the slum’s growing population. F. Apart from a chicken that had fallen in and had been rescued, the well seemed harmless.