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Given a multiple alignment of three sequences, the sum of scores is calculated as the sum of the dissimilarity scores of every pair of sequences at each position.

Given a multiple alignment of three sequences, the sum of scores is calculated as the sum of the dissimilarity scores of every pair of sequences at each position. Correct Answer False

Given a multiple alignment of three sequences, the sum of scores is calculated as the sum of the similarity scores of every pair of sequences at each position. The scoring is based on the BLOSUM62 matrix. If the total score for the alignment is 5, which means that the alignment is 25 = 32 times more likely to occur among homologous sequences than by random chance.

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Progressive alignment methods use the dynamic programming method to build an MSA starting with the most related sequences and then progressively adding less related sequences or groups of sequences to the initial alignment.
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