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Infection of HIV-1 is initiated by the binding of gp120 to CD4 and a co-receptor on host cells, triggering large scale conformational changes in gp41 that eventually lead to membrane fusion.

Infection of HIV-1 is initiated by the binding of gp120 to CD4 and a co-receptor on host cells, triggering large scale conformational changes in gp41 that eventually lead to membrane fusion. Correct Answer True

The above statement is true. Infection of HIV-1 is initiated by the binding of gp120 to CD4 and a co-receptor on host cells, triggering large scale conformational changes in gp41 that eventually lead to membrane fusion. Therefore, the gp120 protein is of immense importance to HIV-1.

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