In the laboratory testing of new drugs

A The LD50 (ratof a drug is the dose that will kill 50 percent of the rats injected.
B Teratogenicity tests examine the potential of a drug to produce congenital abnormalities if given during pregnancy.
C The carcinogenic potential of a drug is obvious when administered for about one-third of the lifespan of an animal.
D Information on carcinogenicity of compounds is obtained from acute toxicity tests.
E The therapeutic index is an indication of the potency of a drug

Correct Answer: The LD50 (ratof a drug is the dose that will kill 50 percent of the rats injected., Teratogenicity tests examine the potential of a drug to produce congenital abnormalities if given during pregnancy., The carcinogenic potential of a drug is obvious when administered for about one-third of the lifespan of an animal.

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