Regarding familial adenomatous polyposis
A
Manifest with numerous adenomatous polyps by age 15 years
B
Vast majority develops colorectal cancer by 50 years of age
C
Upper gastrointestinal tract is rarely involved
D
It is an autosomal recessive disorder
E
There is no extra-intestinal features
Correct Answer: Manifest with numerous adenomatous polyps by age 15 years, Vast majority develops colorectal cancer by 50 years of age, Upper gastrointestinal tract is rarely involved