Familial adenomatous polyposis MCQ 2+

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• Regarding familial adenomatous polyposis
  ক

  Manifest with numerous adenomatous polyps by age 15 years

  খ

  Vast majority develops colorectal cancer by 50 years of age

  গ

  Upper gastrointestinal tract is rarely involved

  ঘ

  It is an autosomal recessive disorder

  ঙ

  There is no extra-intestinal features
• Familial adenomatous polyposis
  ক

  Leads to adenocarcinoma in untreated case

  খ

  Is diagnosed by detection of 100 polyps in the colon

  গ

  May develop due to new mutation in germline

  ঘ

  Is an autosomal recessive disorder

  ঙ

  Is known as Lynch syndrome