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ICMR published "National Guidelines for Gene Therapy Product Development and Clinical Trails". Which of the following statements are correct about Gene Therapy Product (GTP)? 1. It is defined as any biological entity, having the required gene, that could introduce modifications in the genome for therapeutic benefit. 2. GTPs work by repairing, replacing or deactivating dysfunctional disease-causing genes to restore normal function. 3. As per the New Drugs and Clinical Trial Rules (2019), the GTPs falls under 'new drug' and shall always be deemed as 'new drug'. 4. Thalassemia, Gaucher's disease, Sickle cell anaemia and Haemophilia fall under the genetically inherited disease category. Select the correct answer using the code given below:
Consider the following statements regarding the general symptoms of diseases and choose the correct answer:
1. The charges in the host which serve to recognise the disease are called the signs and symptoms of the disease
2. The sign of a disease is the external appearance of some portion of the pathogen of the host
3. The symptoms are the visible effects which the host plant induces on the parasites
4. Any visible deviation on the host plant from the normal structure and function is called a symptom
In the context of Melioidosis disease, consider the following statements. 1. It is an infectious disease that can infect humans or animals through direct contact with a contaminated source. 2. The disease is caused by the bacterium Burkholderia pseudomallei. 3. It is predominately a disease of temperate climates, especially in parts of China, and Russian Siberia. Which of the statements given above is/are correct?
Which of the following statement/s is/are correct regarding ‘Zika disease’? 1. Zika virus disease is transmitted primarily by Aedes mosquitoes. 2. Till date no vaccine or medicine has been proven effective against Zika disease. 3. Mild fever, skin rash, muscle and joint pain are some of the symptoms of the zika virus disease.
The influence of shape of aggregate in strength and workability of concrete are given below in statements S1, S2, S3 and S4. Which of the statements are correct? S1: Rounded aggregate produces concrete with high workability and low strength. S2: Angular aggregate produces concrete with high workability and low strength. S3: Rounded aggregate produces concrete with low workability and high strength. S4: Angular aggregate produces concrete with low workability and high strength.
Given below are two statements, one labelled as Assertion (A) and the other as Reason (R). Assertion (A): Barani writes, ‘Sultan Muhammad Tughlaq talked as if he hated low-born people more than he hated idols, Nevertheless, I have seen him promoting Najba, the low-born son of a musician, to such an extent that he rose higher in status than many maliks, for Gujarat, Multan and Badaon were put in his charge . . . It was strange how he gave high offices and governments of extensive territories and great provinces to men of low and mean birth’. Reason (R): The Sultan believed in offices being open to talent. He dispensed with whatever considerations of birth had persisted in the administration and appointed low-born persons to the highest offices in the administration. In the context of the above two statements which of the following is correct ?
Match the following: a. Whiptail disease  i. Potato  b. Dieback disease ii. Cauliflower  c. Khaira disease  iii. Citrus d. Early blight disease  iv. Rice
Consider the following pairs: S.No Pollutant Disease 1 Nitrate Blue baby syndrome 2 Cadmium Black foot disease 3 Arsenic Itai-Itai disease 4 Mercury Minamata disease Which of the pairs given above are correctly matched?
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