Myelofibrosis
A
Is characterized by increased number of fibroblasts in the bone marrow
B
Requires trephine biopsy for diagnosis
C
Produces a low neutrophil alkaline phosphatase score
D
Is usually accompanied by splenic atrophy
E
Causes death most frequently by acute leukemic transformation
Correct Answer: Is characterized by increased number of fibroblasts in the bone marrow, Requires trephine biopsy for diagnosis, Produces a low neutrophil alkaline phosphatase score