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A thick layer of Lidocaine & Prilocaine cream is applied to intact skin and covered with an occlusive dressing.
Minor Dermal Procedures: For intravenous cannulation and venipuncture, apply 2.5 grams of Lidocaine & Prilocaine cream over 20 – 25cm2 of skin surface for at least 1 hour.
Major Dermal Procedures: For more painful dermatological procedures involving a larger skin area, apply 2grams of Lidocaine & Prilocaine cream per 10cm2 of skin and allow to remain in contact with the skin for at least 2 hours.
Adult Male Genital Skin: As an adjunct prior to local anesthetic infiltration, apply a thick layer of Lidocaine & Prilocaine cream to the skin surface for 15 minutes. Local anesthetic infiltration should be performed immediately after removal of Lidocaine & Prilocaine cream.
Adult Female Genital Mucous Membranes: For minor procedures on the female external genitalia, such as removal of condylomata acuminata, as well as for use as pretreatment for anesthetic infiltration, apply a thick layer (50 grams) of Lidocaine & Prilocaine cream for 5 to 10 minutes. Occlusion is not necessary for absorption, but may be helpful to keep the cream in place. Patients should be lying down during the Lidocaine & Prilocaine cream application, especially if no occlusion is used. The procedure or the local anesthetic infiltration should be performed immediately after the removal of Lidocaine & Prilocaine cream.
Pediatric Patients: The following are the maximum recommended doses, application areas and application times for Lidocaine & Prilocaine cream based on a child’s age and weight:
- 0 to 3 months or <5 kg: Maximum Total Dose 1 gm, Maximum Application Time: 1 hour
- 3 to 12 months and >5 kg: Maximum Total Dose 2 gm, Maximum Application Time 4 hour
- 1 to 6 years and >10 kg: Maximum Total Dose 10 gm, Maximum Application Time 4 hour
- 7 to 12 years and >20 kg: Maximum Total Dose 20 gm, Maximum Application Time 4 hour
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