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Menopausal vasomotor symptoms: 0.45 mg/day, up to 1.25 mg/day. Attempt to discontinue medication at 3-mth intervals.
Vulvular and vaginal atrophy: 0.3 mg/day.
Female hypogonadism: 0.3.625 mg/day in a cyclical regimen. Add progestin treatment once skeletal maturity is achieved.
Female castration, Primary ovarian failure: 1.25 mg/day in a cyclical regimen. Palliation in prostate carcinoma 1.25.5 mg 3 times/day.
Osteoporosis prophylaxis in postmenopausal women: Initial: 0.3 mg/day in a cyclical or continuous regimen depending on patient's condition.
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