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The volume and rate of infusion of dextrose solution will depend upon the requirements of the individual patient and the judgement of the physician.

The maximum rate at which dextrose can be infused without producing glycosuria is 0.5 gm/kg/hr.

The usual recommended flow rate for adult is 105 drops per minute infused intravenously. 

Intravenous-

Hyperkalaemia:

  • Adult: 250 g combined with 10 units of regular insulin, administered over 300 minutes; may repeat if necessary. Alternatively, 25 g combined with 50 units of regular insulin infused over 5 minutes; may repeat if necessary.
  • Child and infants: 0.5 g/kg (using 25% or 50% solution) combined with regular insulin (1 unit for every 4 g dextrose given); infuse over 2 hr, may repeat if necessary.

Intravenous-

Hypoglycaemia:

  • Adult: 105 g (4000 ml of 25% solution or 200 ml of 50% solution). Doses may be repeated in severe cases.
  • Child: ≤6 mth: 0.25.5 g/kg/dose; >6 mth: 0.5 g/kg/dose. Doses may be repeated in severe cases. Max: 25 g/dose.

Oral-

Hypoglycaemia:

  • Adult: 100 g as single dose; may repeat in 10 min if needed.
  • Child: >2 yr: 100 g as single dose; may repeat in 10 min if needed.

It should not be administered by SC or IM route. Dextrose should be infused through the largest available peripheral vein.

 

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