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In enzymology, a tRNA-uridine aminocarboxypropyltransferase is an enzyme that catalyzes the chemical reaction

Thus, the two substrates of this enzyme are S-adenosyl-L-methionine and tRNA uridine, whereas its two products are 5'-methylthioadenosine and tRNA 3--uridine.

This enzyme belongs to the family of transferases, specifically those transferring aryl or alkyl groups other than methyl groups. The systematic name of this enzyme class is S-adenosyl-L-methionine:tRNA-uridine 3-transferase.

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